23andMe to create a skin disorders treatment with Almirall

23andMe to create a skin disorders treatment with Almirall

DNA Test Provider News, science
is 23andme pivoting its business? You Paid $99 for 23andMe to Analyze Your DNA. Now, Your DNA will be Used for Treatments.  23andMe, the world’s leading health-related DNA test kit manufacturer, recently announced that it has licensed a therapeutic treatment for skin inflammation - based on the DNA data it has collected from its 10 million customers.  While 23andMe does give you the option to opt-out of research efforts, nearly 80% of customers opt-in. This means that 23andMe has a pool of nearly 8 million DNA samples to analyze and draw conclusions from! (AncestryDNA Vs. 23andMe comparison shows they are the global leaders in terms of customer numbers).  With this data, 23andMe has been able to create a theoretical treatment for skin disorders. Let’s take a look at how this treatment…
Read More
A Genetic Test for SARS-CoV-2 Infection Risk?

A Genetic Test for SARS-CoV-2 Infection Risk?

science
The current COVID-19 pandemic has spread to nearly every country. At the time of this writing, over 1,000,000 people have been infected by the SARS-CoV-2 virus at the center of the pandemic. The damage to the global health and economy (including the impact of coronavirus on unemployment) is unprecedented.  However, nearly 95% of cases only show mild symptoms and most of these people recover. For the other 5%, symptoms can lead to severe respiratory distress, hospitalization, and death. There are many, many reasons that some people are more susceptible to the virus than others. Poor lung health, bad circulation, and lowered immune function have all been fingered as potential culprits for increased viral susceptibility.  However, researchers at 23andMe also believe that some answers may be found in the genome. Your…
Read More
Coronavirus and Your DNA

Coronavirus and Your DNA

science
Quarantined from Coronavirus? Learn how DNA ancestry techniques can determine where the virus came from. To start, we would just like to say that we truly hope you, your family, and your friends are all taking care during this pandemic. Further, this article contains no advice on how to prevent the spread of viruses or any specific recommendations for those with immediate, pressing questions. You can find answers to most of those questions from your local health departments. Instead, this article is intended for all of the quarantined science nerds out there seeking comfort in the miracle of science (and how you can experience the miracle yourself!).  Specifically, we’ll be looking at how science can tell us where the coronavirus originated, and how you can use the same powerful technology…
Read More
Are you being ripped off? Correlation vs. Causation in Genetic Tests

Are you being ripped off? Correlation vs. Causation in Genetic Tests

Genealogy, science
Updated August 18 with information about Microbiome testing. For those of you new to the genetic testing field, you should first have a solid understanding of correlation versus causation. The distinction between these scientific terms can allow you to get the most out of your genetic tests, and truly understand how your genes affect your health and lifestyle. While the two terms are related, the difference between correlation and causation is similar to the difference between an educated guess and knowing the answer outright. Knowing whether a genetic report is based on correlation or causation makes a big difference in how serious you should take the results (or how good is the test kit).   First, let’s get an understanding of what correlation and causation actually are. Correlation A correlation…
Read More
Are Telemore DNA Tests Reliable?

Are Telemore DNA Tests Reliable?

Genealogy, science
What are Telomeres? Telomeres are distinctive structures, regionized in DNA strands which are located at each end. They are caps to prevent the chromosome from deteriorating, somewhat like the plastic shells of a shoelace. They have a repetitive, short DNA sequence and are many kilobases in length. The Telomeres also prevent fusing with neighbouring chromosomes. Telomeres derives from the two Greek words “telos” which means “end” and ”meros” which means “part”. The sequence in human Telomeres is TTAGGG, which is repeated around 2,500 times. There are 194 Telomeres in a human cell, 4 for each of the 46 chromosomes. What are Telomere tests As cells age, its Telomeres gradually become shorter. The average cell will divide around 60 times before it dies. As the cell divides, the Telomeres of course…
Read More
DNA Data Testing: How Accurate and Useful?

DNA Data Testing: How Accurate and Useful?

science
DNA testing kits are an amazing piece of technology. Just imagine, in 2003 the Human Genome Project was completed. It took scientists BILLIONS of dollars and an entire DECADE to complete. Today, you can have important pieces of your DNA tested for less than $100, or get your entire genome sequenced for less than $1000. Not only this, but you can get the results from the comfort of your home, after sending in a simple DNA sample from your cheek cells. Companies like 23andMe, Ancestry, and Veritas Genetics have sprung up to bring the power of DNA testing to the masses. These companies offer a number of different tests, ranging from what your genetics can tell you about your genealogy to the various disease risks you may carry due to…
Read More
23andMe Polygenic Risk Scores

23andMe Polygenic Risk Scores

science
When it comes to innovating genetic testing, 23andMe is always at the forefront of science. Not only were they one of the first companies on the genetic testing scene, but they were one of the first to get their breast-cancer screening test approved by the FDA. The company is partially owned by Google Ventures, Google’s start-up investment wing. This gives 23andMe a technological edge over other companies, and they are often the first on the market with a new offering. Recently, 23andMe started offering a polygenic risk score for diabetes, offering another thing to differentiate it in the 23andMe vs Ancestry battle and marking it as a top leader in both ancestry testing and health testing. [su_box title="Recent comment from the UK Health Minister" style="soft" title_color="#262424"]The UK Health Minister has…
Read More
The Truth about Genetics and Disease: Is it Nature, or Nurture?

The Truth about Genetics and Disease: Is it Nature, or Nurture?

science
The FDA recently approved 23andMe’s genetic test which screens for breast cancer. The move was heralded as a great advancement in the field of direct-to-consumer genetic testing. Many people purchased the test, hoping it would reveal whether or not they would get breast cancer. However, in its approval, the FDA also mentioned some serious limitations of the test. For one, it only tests for 3 of thousands of known mutations. If any other spot in the BRCA gene is mutated, the test would show negative when you actually do have a higher risk. But more importantly than that, the BRCA mutations they screen for are “rarely found” in the general population. Even those of Ashkenazi Jewish descent, who experience a higher rate of the mutation, only find it in around…
Read More
Home DNA Paternity Test

Home DNA Paternity Test

Genealogy, science
Can Direct-to-Consumer Genetics Tests Provide Accurate Results? First, How Does Paternity Testing Work? Paternity testing, like other forms of familial testing (sibling, maternal, etc.) is a relatively straightforward practice. Other forms of DNA analysis rely on understanding the genes involved and their relationship with disease. In paternity testing, scientists are simply checking to see if the DNA matches in various locations. In this article we will focus on home DNA paternity tests. To understand how this process can identify someone as a direct family member, you must understand a little bit about genetics. A human starts as two different cells, the sperm and the egg. Inside of these cells is exactly half of the DNA necessary to create a human. Both cells contain 23 chromosomes, or parts of DNA. Half Mom,…
Read More
Autosomal testing vs Mitochondrial testing (mtDNA) vs Y-Chromosome testing

Autosomal testing vs Mitochondrial testing (mtDNA) vs Y-Chromosome testing

Genealogy, science
When going over your options for a direct-to-consumer DNA test, the options can be overwhelming. Between the different companies available, testing methods used, and services provided, it can be hard to choose a company and plan with any confidence. In terms of testing methods alone, there are several approaches different companies take to analyze your genetics. In general, companies tend to analyze up to 3 different parts of your genetic code. The majority of companies test your Autosomal Chromosomes. These chromosomes represent a majority of your DNA. They account for 22 of the 23 chromosomes. The 23 chromosome is your Sex Chromosome, and contains two forms: X and Y. Females have a pair of X chromosomes, while men have an X and a Y. Because the Y is always passed down…
Read More